Alternate Name:Celebrex
Description:Oradentafil is used to treat female sexual dysfunction. Oradentafil is also used to treat pulmonary arterial hypertension. Oradentafil is also used to treat a rare form of heart rhythm disorder, angina (chest pain).Adjunct TreatmentOradentafil is a selective serotonin reuptake inhibitor (SSRI) or an antihypertensive that can be used as a partial or complete class orunct at doses up to 200 mg PO twice daily or 200 mg PO six times daily for 10 days. Oradentafil is typically used as monotherapy or in combination with other antihypertensive agents.AdministrationThe usual initial dose is 200 mg PO twice daily for 5 days. The dosage may be increased to a maximum dose of 400 mg PO once daily in increments of 2 days by increments of 2 days.Oradentafil should be taken with or without food. Do not take this medication in any form to avoid an upset stomach or stomach that is more upset than normal. If stomach upset occurs while taking this medication, eat an additional half of the meal, and take your medicine at regular intervals. If you miss a dose, take your usual dose.Storage:Store the drug in a closed container at room temperature, away from heat, moisture, and direct light, and keep out of the reach and sight of children. If you are taking this medication to treat angina, do not open the container or touch the contents to the medication or any surface, and do not use a household teaspoon. Oradentafil should be taken with food or milk and should be taken at regular intervals. Oradentafil may take longer to show full effect if you take it longer than usual.Drug InteractionsThis medication may interact with other drugs you are taking for heart rhythm disorder, including:
GeneralThis treatment is not recommended for children as they may be more sensitive to the effects of this drug and should be adjusted according to the child's weight and age. If a child is given this treatment, your child should be advised that the drug may worsen conditions in them. Consult your doctor before you use this medication to check if your child is still growing. This medication does not affect the menstrual cycle or increases the likelihood of pregnancy. Consult your doctor before you use this medication to check if you are at an increased risk of becoming pregnant. If the menstrual cycle does not return within a few days of treatment, your child should be treated as directed by your doctor.
References NHS We can prescribe this drug in many ways. Some of these ways may include:- Use of this medication for the relief of pain caused by headache or arthritis.- Use of this medication for the relief of pain caused by menstrual cramps (such as heavy or long periods of heavy lifting, abnormal menstrual cycles, or breakthrough bleeding)..- Treats erectile dysfunction. Information on this medication is available in the public domain in the form of a printed drug pack. This drug is not recommended for children as they may be more sensitive to the effects of this medication and should be prescribed before or after pregnancy.- Follow the dosage instructions printed on the pack. The amount and direction for using this medication will depend on the child's weight and age.- Use this medication as directed by your doctor, usually once per day. If you miss a dose, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not use two doses at one time.References AIDS Drugs are available in many forms and are available in many forms and at a different strength than Oradentafil. The dosage forms of this medication are listed below. Dosages for oral use are also available from many or the online drugstores. Please click for dosage forms.References AIDS Drugs Drugs are available in many forms and are available in many forms and at a different strength.Celebrex 100mg Tablet contains the active ingredient Celecoxib. It belongs to the family known as non-steroidal anti-inflammatory drugs (NSAID), and specifically a sub-group known as cyclooxygenase-2 (COX-2) inhibitors. It is used in adults for the relief of signs and symptoms of rheumatoid arthritis, osteoarthritis, and ankylosing spondylitis. In conditions like rheumatoid arthritis and osteoarthritis, excess production of prostaglandins by your body can lead to pain and inflammation. Celebrex 100mg Tablet works by decreasing the production of prostaglandins, effectively reducing pain and inflammation.
Do not take Celebrex 100mg Tablet if you are allergic to Celebrex 100mg Tablet or any of its ingredients. Inform your doctor if you had reactions to sulfonamide medicines, suffer from ulcers or bleeding in the stomach or intestines, or experienced adverse reactions to NSAID medications like aspirin.
Before starting the treatment, inform your doctor because it is recommended to not take this medicine if you are pregnant or are breastfeeding. Do not take this medicine if you have severe liver or kidney disease, have inflammatory intestinal conditions, or have heart-related issues such as heart failure, heart disease, or circulation problems. Additionally, if you have had surgeries on leg arteries or have a history of blood circulation problems, this medicine usage should be avoided. Celebrex 100mg Tablet contains lactose. If you are sugar intolerant, consult your doctor before using this product. This medicine is for adults only, it is not for use in children.
Inform your doctor about if you have a history of stomach or intestinal ulcers or bleeding (avoid if currently present), are on acetylsalicylic acid or antiplatelet therapies, use blood clotting or corticosteroid medications, or simultaneously use other non-acetylsalicylic NSAIDs like ibuprofen.
Report your doctor if you have conditions such as smoking, diabetes, high blood pressure, high cholesterol, compromised heart, liver, or kidney function, fluid retention, dehydration, past severe allergic reactions to medications, ongoing infections, or are over 65 years old. Monitoring may be necessary. Notably, Celebrex 100mg Tablet could mask fever or infection signs. Remember, alcohol combined with NSAIDs may increase gastrointestinal risks.
Show/Uses Home/LargoCelebrex 100mg Tablet is used for treating signs and symptoms of rheumatoid arthritis, osteoarthritis, and ankylosing spondylitis, but it also acts as a pain reliever and an adjuvant in some cases. This medicine reduces inflammation and pain during surgery, including coronary artery bypass graft (CABG) surgery. Celebrex 100mg Tablet can be used in the relief of signs and symptoms of NSAID conditions such as rheumatoid arthritis, osteoarthritis, and ankylosing spondylitis. Celebrex 100mg Tablet can be taken with or without food.
Common side effects of Celebrex 100mg Tablet include diarrhea, loose stools, nausea, and vomiting. Seek your doctor's advice if any of these effects persist or become bothersome.
Consider taking Celebrex 100mg Tablet with a meal, especially if you have a meal on hand. A low-fat meal might reduce the possibility of side effects. Celebrex 100mg Tablet can reduce the absorption of certain nutrients, which may lead to increased calorie intake and possibly tooth loss. Additionally, taking Celebrex 100mg Tablet with a meal might help improve your body's ability to absorb fat.
Show/HealthCelebrex 100mg Tablet is not intended for use in children. It is not known if this medicine is safe and effective in adults under 18 years of age. Celebrex 100mg Tablet should be used in the treatment of signs and symptoms of rheumatoid arthritis, osteoarthritis, and ankylosing spondylitis only if prescribed by a doctor, and for the relief of the pain and inflammation associated with these conditions. Do not use Celebrex 100mg Tablet if you are pregnant or breastfeeding, unless your doctor has told you to. Celebrex 100mg Tablet is not intended for use in women. It may also not be suitable for use in children under the age of 18 years in patients allergic to aspirin or other NSAIDs, or in those who have had a stomach or intestinal ulcer, or in those with a history of ulcers or bleeding in the stomach or intestines. This medicine should not be used in children below the age of 18 years as it may cause adverse effects. Advise your doctor or pharmacist if you have any questions about the use of Celebrex 100mg Tablet.
NEW YORK —The drugmaker Pfizer has agreed to pay $75 billion to settle lawsuits claiming the painkiller has caused heart attacks and other serious health problems. The government has not disclosed the amount. The company said it will pay a $2.5 billion settlement. The company said the settlement includes a $6 billion payment by its employees.
The settlement includes more than $1 billion in payments by its employees, the companies said. That amount was included in the amount reached last month by the New York attorney general's office.
The drug maker said its largest lawsuit was in 2015, when it filed for a class-action lawsuit against Pfizer alleging that it had engaged in a marketing fraud and deceptive business practice. The New York attorney general's office said the settlement is expected to be paid by the company by the end of the year.
The lawsuits, which were filed in federal court, allege that Pfizer's marketing practices caused a heart attack and a heart attack in 2004. The company, which makes Celebrex, pleaded guilty in September 2012 to the federal marketing fraud charges and agreed to pay a $5 billion fine and a $4.9 billion settlement. It will pay an additional $1 billion in damages.
The suit was filed in federal court in New Jersey and involved nearly $5 billion in damages, including a $1.3 billion settlement. The companies also have settled with several states, including New York, which has taken legal action against Pfizer and related pharmaceutical companies.
The New York attorney general's office said the settlement resolves allegations that the company and its executives have been misleading consumers and selling false information to doctors.
It is the first time the company has reached a settlement over a class-action lawsuit.
The suit was filed on April 10 and is a suit filed in state court in Delaware and brought by a plaintiff in federal court in Brooklyn. The complaint alleges that Pfizer made false, misleading and deceptive marketing claims to doctors.
In a settlement statement, Pfizer, Inc. said, "Pfizer is committed to vigorously challenge the Company's conduct in this matter and to pursue appropriate enforcement actions to ensure the integrity of the Company's business. We will pay any and all costs and expenses related to this litigation related to the successful resolution of this case."
The settlement includes $5 billion in payments by Pfizer to its employees, the companies said. Pfizer said the settlement is expected to be paid by the end of the year.
The New York attorney general's office said the company has not agreed to settle the suit.
The government was the first to file a new lawsuit against the pharmaceutical industry, and in October 2015, it filed for a class-action lawsuit against the drug maker. The government has filed a third-party lawsuit alleging that the drug maker did "promulge, directly or indirectly, false and misleading statements and information about physicians, consumers, health care providers, and patients about Celebrex and other pain-relief drugs, including other non-steroidal anti-inflammatory drugs, and other products and drugs that were used to treat arthritis."
The suit claims that the company's marketing of Celebrex, a COX-2 inhibitor, led to a heart attack and a heart attack in 2004.
In the first suit, Pfizer says, the company did not disclose any of its products to doctors and doctors did not adequately warn consumers about the risks.
The company also says that Celebrex "promises or indicates that it is a safe and effective treatment for osteoarthritis or rheumatoid arthritis," which it claims is caused by its COX-2 inhibitor.
In the second suit, the company says that it did not adequately warn consumers about the dangers of using Celebrex to treat arthritis or other pain.
In addition, the company says, "Pfizer is a leader in the treatment of serious medical conditions, including osteoarthritis, acute myocardial infarction, acute exacerbation of chronic obstructive pulmonary disease, and chronic kidney disease."
The first and second suits also allege that Pfizer and its doctors knew of the dangers of Celebrex and were aware of the risks and took corrective measures.
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